I asked my doc how she felt about Diamox, etc., when I saw her a few days ago, so we looked it up in one of her guides(reminded me of a phone book!) It was interesting that the "general" perscription was for 500mg, so using that dosage as a benchmark for side effects(Ken made a funny remark about how miserable that dosage is somewhere else)One would back way off of liberally handing ou that med for a recreational activity. The same could be said for Dex. My doc mentioned to me that if one "pre" needs Dex to recreate, than one needs to find a new activity -- Dex is to be used only as an emergency intervention, not as a passport to play...(yikes!)