Yeah I live in Bay Area and started in mariposa (about 1800 ft elevation) the night before Dana hike. Drove around 8k in 2.5 hours and returned home back to sea level in 4 hours from 12k elevation hike. That could be a too much elevation back and forth in a day.

I got the diamox med from my doctor and will be taking twice a day from 5 days before hike. Hope it helps