I used Oxygen Plus on Mt. Whitney and the results were inconclusive. I didn't notice anything different. There was no evidence that I even inhaled pure oxygen. Maybe if they had a different nozzle the oxygen would transfer better?

They don't claim that their product is useful for dealing with thin air at altitude, which I think they would if it was effective.

The cans weigh almost nothing. I just consider this a one-time experiment that I may or may not try again.