You need to call the Wilderness Permit number: 760-873-2483
Their phone system is low-tech, there is no wait queue. If you don't get through, you have to hang up and call again. Be persistent, and you will reach someone.

Unfortunately, they don't allow switching trip leaders. But I would call, and see if there are any options.

If he cancels his permit, the slots will show up on recreation.gov at a random time in the next 24 hours. If you were watching for them to show up, you might get lucky and be able to grab them.

Next time, add an alternate leader!!!