1. Just so you know, driving from Las Vegas is only 10 miles farther, and you are guaranteed better scenery and no chances of traffic jams. Seeing Death Valley is a treat. Seeing Los Angeles... not so much.
At least check flight connections and prices.
2. Hiking all the way to 12k with overnight gear on your first day, and sleeping, is the surest way to invite AMS to hit at least one in your party. I'd save the hard day for the summit day, and stop at Outpost. But it's your hike, I've said enough.
