Lawnerd,
We took 125 mg Diamox twice a day starting the first day in altitude and continued until we had descended on Kilimanjaro. It worked well. Check with your MD. It's really important to drink lots of fluids and eat! Diamox is a diuretic and it will make you urinate. It also has a side effect of pins and needles. Also, take your time on the trail. A slower hike helps you acclimate. We too only have Friday - Sunday. My boss wouldn't give me any more days off. We plan on heading to Whitney Portal on Thursday night. Hope that helps.
Chickadee