ONC is out of the pic to the southeast, and Commercial Street is way out to the SE. That's Charter Street running through the middle, and Storrow drive to the North of that.
Rod scores right up there with Sarah Palin on the history. That's Copp's Hill, now a cemetery where the guy who actually hung the lanterns is buried, and Charlestown, the famous "opposite shore" where Paul Revere awaited the signal, and where the British landed for the Battle of Bunker (Breed's) Hill two months later.
Navy Yard, however is probably the most commercial enterprise in the shot. Now supports exactly one ship, also a Palin favorite.